Mal-PEG8-Val-Cit-PAB-MMAF
Mal-PEG8-Val-Cit-PAB-MMAF is a drug-linker conjugate for ADC. Mal-PEG8-Val-Cit-PAB-MMAF contains a cleavable ADC linker and a potent tubulin inhibitor MMAE.
Product Specifications
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-peg8-val-cit-pab-mmaf.html
Purity
99.97
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C=CC1=O)=O)N[C@H](C(N[C@H](C(NC2=CC=C(COC(N([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(N3[C@]([H])([C@@H]([C@H](C(N[C@@H](CC4=CC=CC=C4)C(O)=O)=O)C)OC)CCC3)=O)OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)C)=O)C=C2)=O)CCCNC(N)=O)=O)C(C)C
Molecular Formula
C81H129N11O24
Molecular Weight
1640.95
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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