PROTAC BRD4-DCAF1 degrader-1
PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. (Pink: BRD4-DCAF1 ligand ; Black: linker (HY-126976) ; Blue: E3 ligase ligand (HY-15846) ).
Product Specifications
CAS Number
3036944-87-0
UNSPSC
12352005
Target
Epigenetic Reader Domain; PROTACs
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/protac-brd4-dcaf1-degrader-1.html
Smiles
CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCOCCOCCOCCOCCOCCCC4=CC=C(C=C4)C(C5=C(C6=C(C(F)=CC=C6F)C)C(C(N[C@H](C7=CC(Cl)=CC=C7)CC(N)=O)=O)=CN5)=O)=O)C8=NN=C(C)N28
Molecular Formula
C60H64Cl2F2N8O9S
Molecular Weight
1182.17
References & Citations
[1]Lewis Dale Pennington, et al. Protein degraders and uses thereof. WO2024092009A1. 2024-05-02.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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