CCR8 antagonist 3
Product Specifications
UNSPSC Description
CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC50 value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability[1].
Target Antigen
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ccr8-antagonist-3.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC=C1OC2=CC=CC=C2CN3CCC4(CCN(C(C5=CC=CNC5=O)=O)CC4)CC3
Molecular Weight
487.59
References & Citations
[1]Stephen Connolly, et al. Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases. WO2006107254A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-160647/CCR8-antagonist-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-160647/
Clinical Information
No Development Reported
CAS Number
912463-57-1
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