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CCR8 antagonist 3

CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC50 value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability[1].

Product Specifications

CAS Number

[912463-57-1]

UNSPSC

12352005

Target

CCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ccr8-antagonist-3.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=CC=C1OC2=CC=CC=C2CN3CCC4(CCN(C(C5=CC=CNC5=O)=O)CC4)CC3

Molecular Formula

C29H33N3O4

Molecular Weight

487.59

References & Citations

[1]Stephen Connolly, et al. Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases. WO2006107254A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCR8

Curated Selection

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