CCR8 antagonist 3
CCR8 antagonist 3 (compound 2) is a CCR8 antagonist with an IC50 value of 0.062 µM. CCR8 antagonist 3 shows human microsomal stability[1].
Product Specifications
CAS Number
[912463-57-1]
UNSPSC
12352005
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ccr8-antagonist-3.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC=C1OC2=CC=CC=C2CN3CCC4(CCN(C(C5=CC=CNC5=O)=O)CC4)CC3
Molecular Formula
C29H33N3O4
Molecular Weight
487.59
References & Citations
[1]Stephen Connolly, et al. Novel diazaspiroalkanes and their use for treatment of ccr8 mediated diseases. WO2006107254A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR8
Curated Selection
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