Timonacic

Timonacic (1,3-Thiazolidine-4-carboxylic acid) is an orally active thiol antioxidant. Timonacic has anti-aging and anti-hepatotoxic effects. Timonacic has a LD50 of 400 mg/kg for mice. Timonacic can be used in the research of liver diseases, gastrointestinal diseases, and cancer[1][2].

Product Specifications

CAS Number

[444-27-9]

Product Name Alternative

1,3-Thiazolidine-4-carboxylic acid

UNSPSC

12352005

Hazard Statement

H301, H312+H332, H315, H319, H335

Target

Amino Acid Derivatives

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Timonacic.html

Concentration

10mM

Purity

98.0

Solubility

DMSO : 6 mg/mL (ultrasonic) |H2O : 14.29 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1NCSC1)O

Molecular Formula

C4H7NO2S

Molecular Weight

133.17

Precautions

H301, H312+H332, H315, H319, H335

References & Citations

[1]Bakry RS, et al. Spectrophotometric investigation of the formed chelate between timonacic and palladium (II) and its analytical applications. J Pharm Biomed Anal. 1998 May;17 (1) :95-101.|[2]H U Weber, et al. Thiazolidine-4-carboxylic acid, a physiologic sulfhydryl antioxidant with potential value in geriatric medicine. Arch Gerontol Geriatr. 1982 Dec;1 (4) :299-310.