Quinocetone (Standard)
Quinocetone (Standard) is the analytical standard of Quinocetone (HY-123581) . This product is used for research and analytical purposes. Quinocetone is an orally active animal feed additive used to increase the meat production of livestock and poultry. Quinocetone exhibits antibacterial activity against a variety of pathogenic microorganisms. Quinocetone exhibits tissue-specific (liver, lymphocyte) toxicity. Quinocetone induces autophagy in cells through the ATF6/DAPK1 pathway. Quinocetone activates the NF-κB and iNOS pathways, leading to cell apoptosis, hepatocyte vacuolar degeneration and fibrosis. Quinocetone can inhibit Nrf2/HO-1 and induce the generation of reactive oxygen species (ROS), leading to oxidative stress and DNA damage.
Product Specifications
CAS Number
[81810-66-4]
UNSPSC
12352005
Hazard Statement
H315, H319, H335, H341
Target
Antibiotic; Apoptosis; ATF6; Autophagy; Bacterial; DAPK; NF-κB; NO Synthase; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference compound
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/quinocetone-standard.html
Purity
97.94
Smiles
O=C(C1=C(C)[N+]([O-])=C2C=CC=CC2=[N+]1[O-])/C=C/C3=CC=CC=C3
Molecular Formula
C18H14N2O3
Molecular Weight
306.32
Precautions
H315, H319, H335, H341
References & Citations
[1]Zhao-Ying Liu, et al. The Metabolism of Carbadox, Olaquindox, Mequindox, Quinocetone and Cyadox: An Overview. Med Chem. 2013 Dec;9(8):1017-27.
Shipping Conditions
Room Temperature
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
No Development Reported
Available Sizes
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