SJB2-043
SJB2-043 is an inhibitor of the native USP1/UAF1 complex with IC50 of 544 nM.
Product Specifications
CAS Number
[63388-44-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/SJB2-043.html
Purity
99.52
Solubility
DMSO : 3.33 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N=C(C3=CC=CC=C3)O2)C(C4=CC=CC=C41)=O
Molecular Formula
C17H9NO3
Molecular Weight
275.26
Precautions
H302, H315, H319, H335
References & Citations
[1]Mistry H, et al. Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther. 2013 Dec;12 (12) :2651-62.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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