DiZPK (hydrochloride)

DiZPK hydrochloride is a structural analog of pyrrolysine (Pyl), acting as a photocrosslinker for identifying direct protein-protein interactions in living prokaryotic and eukaryotic cells.

Product Specifications

CAS Number

[2349295-23-2]

UNSPSC

12352005

Hazard Statement

H228-H315-H319

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dizpk-hydrochloride.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : 8.33 mg/mL (ultrasonic; warming)

Smiles

N[C@H](C(O)=O)CCCCNC(NCCCC1(N=N1)C)=O.Cl

Molecular Formula

C12H24ClN5O3

Molecular Weight

321.80

Precautions

P210-P240-P241-P264-P280-P302+P352-P305+P351+P338-P362+P364-P370+P378

References & Citations

[1]Zhang M, et al. A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance. Nat Chem Biol. 2011 Sep 4;7 (10) :671-7.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Citation 01

Mol Cell. 2022 Sep 15;82 (18) :3453-3467.e14.|Mol Cell. 2022 Sep 15;82 (18) :3453-3467.e14.|SSRN. 2025 Mar 14.|STAR Protoc. 2020 Sep 15;1 (3) :100109.