Fabomotizole
Fabomotizole (CM346) is an insecticide with anxiolytic, antianxiety, and neuroprotective activities and a substrate of p-glycoprotein. Fabomotizole inhibits the ST-segment depression induced by isoproterenol in a rat model of acute subendocardial ischemia. Fabomotizole also inhibits Giardia lamblia and has the potential to inhibit giardiasis. Fabomotizole also targets Sigma1R, NRH:quinone reductase 2 (NQO2), and MAO-A to exert anxiolytic effects[1][2][3].
Product Specifications
CAS Number
173352-21-1
Product Name Alternative
CM346
UNSPSC
12352005
Hazard Statement
H302
Target
Monoamine Oxidase; Parasite; P-glycoprotein; Sigma Receptor
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Fabomotizole.html
Purity
98.31
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCOC1=CC=C2C(N=C(SCCN3CCOCC3)N2)=C1
Molecular Formula
C15H21N3O2S
Molecular Weight
307.41
Precautions
H302
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
MAO-A; Sigma 1 Receptor
Available Sizes
Frequently Asked Questions
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