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Zaltidine (dihydrochloride)

Zaltidine (CP-5736) dihydrochloride is a highly specific H2 receptor antagonist with antisecretion activity. Zaltidine dihydrochloride reduces the stimulant effect of histamine on gastric acid secretion by binding to histamine H2 receptors on gastric parietal cells, thus reducing gastric acid production. Zaltidine dihydrochloride can be used in the study of gastric acid-related diseases such as duodenal ulcers[1].

Product Specifications

CAS Number

90274-23-0

Product Name Alternative

CP-5736 (dihydrochloride)

UNSPSC

12352005

Target

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/zaltidine-dihydrochloride.html

Smiles

NC(NC1=NC(C2=CN=C(C)N2)=CS1)=N.[H]Cl.[H]Cl

Molecular Formula

C8H12Cl2N6S

Molecular Weight

295.19

References & Citations

[1]Laferla G, et al. The antisecretory effects of zaltidine, a novel long‐acting H2‐receptor antagonist, in healthy volunteers and in subjects with a past history of duodenal ulcer[J]. British journal of clinical pharmacology, 1986, 22 (4) : 395-399.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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