Fagaronine (chloride)
Fagaronine chloride is an alkaloid with inhibitory activity against reverse transcriptase and topoisomerase I. Fagaronine chloride can effectively inhibit the reverse transcriptase of RSii tumor virus at a concentration of 6-60 μg/mL. Fagaronine chloride rapidly blocks the synthesis of DNA polymerase by interacting with the template primer. Fagaronine chloride has shown anti-tumor potential, especially in the study of retroviral infection[1].
Product Specifications
CAS Number
52259-64-0
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fagaronine-chloride.html
Smiles
C[N+]1=CC2=CC(OC)=C(C=C2C3=C1C4=CC(OC)=C(C=C4C=C3)O)OC.[Cl-]
Molecular Formula
C21H20ClNO4
Molecular Weight
385.84
References & Citations
[1]INHIBITION OF RET'ERSE TRANSCRIPTASE ACTII'ITY BY BENZOPHENASTHRIDINE ALKALOIDS
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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