CYM 50769
CYM 50769 is a non-peptidic selective antagonist of neuropeptides B and W receptor 1 (NPBWR1) . CYM 50769 can attenuates the NPW-23-induced cell proliferation in ATDC5. CYM 50769 can be used for researching endochondral bone formation[1].
Product Specifications
CAS Number
[1421365-63-0]
UNSPSC
12352005
Hazard Statement
H302, H413
Target
Neuropeptide B/W Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/cym-50769.html
Purity
98.83
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(OC2=CC=C(OC)C=C2)=C(Cl)C=NN1C3C4=C(C5=C3C=CC=C5)C=CC=C4
Molecular Formula
C24H17ClN2O3
Molecular Weight
416.86
Precautions
H302, H413
References & Citations
[1]Guerrero M, et al. SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists. Bioorg Med Chem Lett. 2013 Feb 1;23 (3) :614-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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