L-Glutamic acid-13C5
L-Glutamic acid-13C5 is the 13C-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Product Specifications
CAS Number
[55443-55-5]
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/l-glutamic-acid-13c5.html
Purity
98.36
Solubility
H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[13C]([13CH2][13CH2][13C@H](N)[13C](O)=O)=O
Molecular Formula
13C5H9NO4
Molecular Weight
152.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
AMPA Receptor; NMDA Receptor
Available Sizes
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