Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Strophanthidin

Strophanthidin is a naturally available cardiac glycoside[1]. Strophanthidin 0.1 and 1 nmol/L increases and 1~100 μmol/L inhibits the Na+/K+-ATPase activities, but Strophanthidin 10 and 100 nmol/L does not affect Na+/K+-ATPase activities in cardiac sarcolemmal[2]. Strophanthidin increases both diastolic and systolic intracellular Ca2+ concentration[3].

Product Specifications

CAS Number

66-28-4

Product Name Alternative

Splitomycin,Erythromycin Cyclocarbonate

UNSPSC

12352005

Hazard Statement

H300+H310+H330

Target

Na+/K+ ATPase

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/strophanthidin.html

Purity

98.53

Solubility

Ethanol : 25 mg/mL (ultrasonic)

Smiles

O=C[C@@]12[C@]3([H])[C@](CC[C@@]1(C[C@@H](O)CC2)O)([H])[C@@]4([C@@](C)([C@@H](C5=CC(OC5)=O)CC4)CC3)O

Molecular Formula

C23H32O6

Molecular Weight

404.50

Precautions

H300+H310+H330

References & Citations

[1]Reddy D, et al. Strophanthidin Attenuates MAPK, PI3K/AKT/mTOR, and Wnt/β-Catenin Signaling Pathways in Human Cancers. Front Oncol. 2020;9:1469. Published 2020 Jan 17.|[2]Su SW, et al. Relationship between cardiotonic effects and inhibition on cardiac sarcolemmal Na+, K+-ATPase of strophan-thidin at low concentrations. Acta Pharmacol Sin. 2003;24 (11) :1103-1107.|[3]Bennett DL, et al. Strophanthidin-induced gain of Ca2+ occurs during diastole and not systole in guinea-pig ventricular myocytes. Pflugers Arch. 1999;437 (5) :731-736.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

T7 Peptide
orb3142352-01 50 mg

T7 Peptide

Sign In for Pricing
View Details
T7 Peptide
orb3142352-02 10 mg

T7 Peptide

Sign In for Pricing
View Details
Abpa sgRNA CRISPR Lentivector (Rat) (Target 2)
K6057503 1.0 µg DNA

Abpa sgRNA CRISPR Lentivector (Rat) (Target 2)

Sign In for Pricing
View Details
Bovine Glutamine Fructose-6-Phosphate Transaminase 2 ELISA Kit
OM617166 96 Strip Well

Bovine Glutamine Fructose-6-Phosphate Transaminase 2 ELISA Kit

Sign In for Pricing
View Details
Anti-SFRS2IP/SCAF11 Antibody Picoband®
A10138-1 100 µg/Vial

Anti-SFRS2IP/SCAF11 Antibody Picoband®

Sign In for Pricing
View Details
Anti-CDH1 / E-cadherin / CD324
C00598-1mg*5 5x 1mg

Anti-CDH1 / E-cadherin / CD324

Sign In for Pricing
View Details