Teriflunomide
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibits pyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
Product Specifications
CAS Number
163451-81-8
Product Name Alternative
A77 1726
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Teriflunomide.html
Purity
99.92
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
C/C(O)=C(C(NC1=CC=C(C=C1)C(F)(F)F)=O)\C#N
Molecular Formula
C12H9F3N2O2
Molecular Weight
270.21
Precautions
H302
References & Citations
[1]Oh J, et al. An update of teriflunomide for treatment of multiple sclerosis. Ther Clin Risk Manag. 2013;9:177-90.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV755922 1.0 µg DNA
WBSCR2 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV-C-term-HA)
Sign In for Pricing
View Details 
orb1095865-01 20 µg
Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial (Active)
Sign In for Pricing
View Details orb1095865-02 100 µg
Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial (Active)
Sign In for Pricing
View Details orb1095865-03 1 mg
Recombinant Human Cytokine receptor common subunit beta (CSF2RB), partial (Active)
Sign In for Pricing
View Details