Z57346765
Product Specifications
UNSPSC Description
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes in PGK1 glycolysis and inhibits PGK1-dependent cell proliferation. Z57346765 exerts inhibitory effects against clear cell renal cell carcinoma (KIRC)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/z57346765.html
Purity
99.55
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OCCNC1=C2C=CC=CC2=NC(NC3=CC=C(C)C=C3)=N1
Molecular Weight
294.358
References & Citations
[1]He Y, et al. Novel inhibitors targeting the PGK1 metabolic enzyme in glycolysis exhibit effective antitumor activity against kidney renal clear cell carcinoma in vitro and in vivo. Eur J Med Chem. 2024 Mar 5;267:116209.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W195984/Z57346765-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W195984/Z57346765-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1016340-64-9
Available Sizes
Curated Selection
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