Nalidixic acid
Nalidixic acid, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria[1].
Product Specifications
CAS Number
[389-08-2]
UNSPSC
12352005
Hazard Statement
H302, H361
Target
Antibiotic; Bacterial; Topoisomerase
Type
Natural Products
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nalidixic-acid.html
Concentration
10mM
Purity
99.97
Solubility
0.1 M NaOH : 10 mg/mL (ultrasonic) |DMSO : 6 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CN(CC)C2=C(C=CC(C)=N2)C1=O)O
Molecular Formula
C12H12N2O3
Molecular Weight
232.24
Precautions
H302, H361
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
Quinolone; Topoisomerase
Available Sizes
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