NU2058
Product Specifications
UNSPSC Description
NU2058 (O6-(Cyclohexylmethyl)guanine) is a potent, competitive and guanine-based CDK inhibitor with IC50s of 17 μM and 26 μM for CDK2 and CDK1. NU2058 has anti-cancer activity.
Target Antigen
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NU2058.html
Purity
99.66
Solubility
DMSO : ≥ 32 mg/mL
Smiles
NC1=NC(OCC2CCCCC2)=C3NC=NC3=N1
Molecular Weight
247.30
References & Citations
[1]Rigas AC, et al. Therapeutic potential of CDK inhibitor NU2058 in androgen-independent prostate cancer. Oncogene. 2007 Dec 6;26(55):7611-7619.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19316/NU2058-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19316/NU2058-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
161058-83-9
Available Sizes
Curated Selection
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