Sanguinarine
Sanguinarine (Sanguinarin), a benzophenanthridine alkaloid derived from the root of Sanguinaria Canadensis, can stimulate apoptosis via activating the production of reactive oxygen species (ROS) . Sanguinarine-induced apoptosis is associated with the activation of JNK and NF-κB.
Product Specifications
CAS Number
[2447-54-3]
Product Name Alternative
Sanguinarin; Sanguinarium; Pseudochelerythrine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Apoptosis; Autophagy
Type
Natural Products
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Sanguinarine.html
Solubility
10 mM in DMSO
Smiles
C[N+]1=CC2=C3C(OCO3)=CC=C2C(C=CC4=C5)=C1C4=CC6=C5OCO6
Molecular Formula
C20H14NO4
Molecular Weight
332.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
Launched
Citation 01
Available Sizes
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