Mal-L-PA-NH-Boc
Mal-L-PA-NH-Boc is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
[1491152-23-8]
Product Name Alternative
MDPR (boc) ; (S) -MALEOYL-DPR (BOC) -OH·DCHA
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-l-pa-nh-boc.html
Purity
99.30
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C=C1)N([C@@H](CNC(OC(C)(C)C)=O)C(O)=O)C1=O
Molecular Formula
C12H16N2O6
Molecular Weight
284.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Robert Lyon, et al. Self-stabilizing linker conjugates. WO2013173337A2.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker
Available Sizes
Curated Selection
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