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Atacicept

Product Specifications

UNSPSC Description

Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease[1][2].

Target Antigen

Others

Type

Inhibitory Antibodies

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/atacicept.html

Purity

99.5

Solubility

10 mM in DMSO

Smiles

[Atacicept]

References & Citations

[1]Gross JA, et, al. TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. impaired B cell maturation in mice lacking BLyS. Immunity. 2001 Aug;15(2):289-302. |[2]Gross JA, et, al. TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. Nature. 2000 Apr 27;404(6781):995-9.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-P99446/Atacicept-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P99446/Atacicept-SDS-MedChemExpress.pdf

Clinical Information

Phase 3

CAS Number

845264-92-8

Available Sizes

Curated Selection

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