DTA
DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase[1][2].
Product Specifications
CAS Number
654-62-6
Product Name Alternative
2,4-Disulfamyl-5-trifluoromethylaniline
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/dta.html
Purity
99.98
Solubility
10 mM in DMSO
Smiles
FC(F)(F)C1=CC(N)=C(S(N)(=O)=O)C=C1S(N)(=O)=O
Molecular Formula
C7H8F3N3O4S2
Molecular Weight
319.28
Precautions
H315, H319, H335
References & Citations
[1]Brørs O, et al. Pharmacokinetics of hydroflumethiazide during repeated oral administration to healthy subjects. Eur J Clin Pharmacol. 1979 May 21;15 (4) :281-6. |[2]Brørs O, et al. Interaction of hydroflumethiazide and 2,4-disulfamyl-5-trifluoromethylaniline with cyclic AMP phosphodiesterase and carbonic anhydrase. Acta Pharmacol Toxicol (Copenh) . 1982 Oct;51 (4) :273-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
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