DTA

DTA (2,4-Disulfamyl-5-trifluoromethylaniline) is a cyclic AMP phosphodiesterase inhibitor that binds to erythrocyte carbonic anhydrase[1][2].

Product Specifications

CAS Number

[654-62-6]

Product Name Alternative

2,4-Disulfamyl-5-trifluoromethylaniline

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/dta.html

Purity

99.98

Solubility

10 mM in DMSO

Smiles

FC(F)(F)C1=CC(N)=C(S(N)(=O)=O)C=C1S(N)(=O)=O

Molecular Formula

C7H8F3N3O4S2

Molecular Weight

319.28

Precautions

H315, H319, H335

References & Citations

[1]Brørs O, et al. Pharmacokinetics of hydroflumethiazide during repeated oral administration to healthy subjects. Eur J Clin Pharmacol. 1979 May 21;15 (4) :281-6. |[2]Brørs O, et al. Interaction of hydroflumethiazide and 2,4-disulfamyl-5-trifluoromethylaniline with cyclic AMP phosphodiesterase and carbonic anhydrase. Acta Pharmacol Toxicol (Copenh) . 1982 Oct;51 (4) :273-7.