NNRT-IN-5
NNRT-IN-5 (compund 10d) is an orally available non-nucleoside reverse transcriptase inhibitor[1].
Product Specifications
CAS Number
[3032803-00-9]
UNSPSC
12352005
Target
Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nnrt-in-5.html
Smiles
CC1=CC(C2=CC=NC=C2)=CC(C)=C1NC3=C(C=NC(NC4=CC=C(C=C4)C#N)=N3)C5=CNN=C5
Molecular Formula
C27H22N8
Molecular Weight
458.52
References & Citations
[1]Huang WJ, et al. Fragment Addition-Based Design of Heteroaromatic-Biphenyl-DAPYs as Potent and Orally Available Non-nucleoside Reverse Transcriptase Inhibitors Featuring Significantly Enhanced Safety. J Med Chem. 2024 Oct 10;67 (19) :17568-17584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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