Aminopicoline
Aminopicoline (Ascensil) is a potent and nonselective inhibitor of NO synthase (NOS) isoenzymes (iNOS, nNOS, eNOS) [1].
Product Specifications
CAS Number
[695-34-1]
Product Name Alternative
Ascensil
UNSPSC
12352005
Hazard Statement
H301+H311+H331, H314, H412
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/aminopicoline.html
Purity
99.99
Solubility
DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
NC1=NC=CC(C)=C1
Molecular Formula
C6H8N2
Molecular Weight
108.14
Precautions
H301+H311+H331, H314, H412
References & Citations
[1]Boer R, et al. The inhibitory potency and selectivity of arginine substrate site nitric-oxide synthase inhibitors is solely determined by their affinity toward the different isoenzymes. Mol Pharmacol. 2000;58 (5) :1026-1034.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ENOS; iNOS; nNOS
Available Sizes
Curated Selection
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