Emodepside (Standard)

Emodepside (Standard) is the analytical standard of Emodepside. This product is intended for research and analytical applications. Emodepside (PF 1022-221) is a cyclooctadepsipeptide with broad-spectrum anthelmintic activity.

O=C(N([C@H](C(O[C@](C(N([C@H](C(O[C@H](CC1=CC=C(N2CCOCC2)C=C1)C(N(C)[C@H](CC(C)C)C(O[C@H](C)C(N(C)[C@@H](CC(C)C)C3=O)=O)=O)=O)=O)CC(C)C)C)=O)([H])C)=O)CC(C)C)C)[C@H](O3)CC4=CC=C(N5CCOCC5)C=C4

[1]Harder A, et al. Mechanisms of action of emodepside. Parasitol Res. 2005 Oct;97 Suppl 1:S1-10.|[2]Buxton SK, et al. On the mode of action of emodepside: slow effects on membrane potential and voltage-activated currents in Ascaris suum. Br J Pharmacol. 2011 Sep;164(2b):453-70.|[3]Kulke D, et al. Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside. PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3401.|[4]Bull K, et al. Effects of the novel anthelmintic emodepside on the locomotion, egg-laying behaviour and development of Caenorhabditis elegans. Int J Parasitol. 2007 May;37(6):627-36.