ω-Conotoxin FVIA
Product Specifications
UNSPSC Description
ω-Conotoxin FVIA is an N-type Ca2+channel (Ca v 2.2)
inhibitor. ω-Conotoxin FVIA reduces mechanical and thermal pain abnormalities
in a rat model of caudal nerve injury. ω-Conotoxin FVIA can be used in the
study of highly effective pain relievers with low side effects
[1].
Target Antigen
Calcium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(NCC(N[C@H]2CO)=O)=O)[C@@H](C)O)=O)N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@H](NC3=O)C(N)=O)=O)CC(N)=O)=O)CC4=CC=C(O)C=C4)=O)C)=O)[C@H](CC)C)=O)CCCNC(N)=N)=O)CO)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]3CCCCN)=O)=O)CO)=O)CCCNC(N)=N)=O)=O)CO)=O)CCCCN)=O)=O)[C@@H](C)O)=O)=O)CCCCN
Molecular Weight
2566.96
References & Citations
[1]Lee S, et al Analgesic effect of highly reversible ω-conotoxin FVIA on N type Ca2+ channels. Mol Pain. 2010 Dec 21;6:97.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Curated Selection
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