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SN40 (hydrochloride)

SN40 hydrochloride is a potent amino acid transport (AAT) inhibitor with Kis of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 hydrochloride can be used for researching anticancer[1].

Product Specifications

CAS Number

2768663-15-4

UNSPSC

12352005

Target

ASCT; EAAT

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sn40-hydrochloride.html

Purity

98.00

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC([C@@H](NC1)C[C@@H]1NCC2=CC=C(C3=CC=CC=C3)C=C2)=O.[H]Cl

Molecular Formula

C18H21ClN2O2

Molecular Weight

332.82

References & Citations

[1]Grewer Christof, et al. Preparation of amino acids as inhibitors of alanine serine cysteine transporter 2. World Intellectual Property Organization, WO2022087630 A1 2022-04-28

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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