SN40 (hydrochloride)
SN40 hydrochloride is a potent amino acid transport (AAT) inhibitor with Kis of 7.29 μM, 2.42 μM, 2.94 μM, 5.55 μM, 24.43 μM and 5.55 μM for rat ASCT2, human ASCT2, EAAT1, EAAT2, EAAC1 and EAAT5, respectively. SN40 hydrochloride can be used for researching anticancer[1].
Product Specifications
CAS Number
2768663-15-4
UNSPSC
12352005
Target
ASCT; EAAT
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sn40-hydrochloride.html
Purity
98.00
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC([C@@H](NC1)C[C@@H]1NCC2=CC=C(C3=CC=CC=C3)C=C2)=O.[H]Cl
Molecular Formula
C18H21ClN2O2
Molecular Weight
332.82
References & Citations
[1]Grewer Christof, et al. Preparation of amino acids as inhibitors of alanine serine cysteine transporter 2. World Intellectual Property Organization, WO2022087630 A1 2022-04-28
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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