L-Glutamic acid-15N, d5
L-Glutamic acid-15N, d5 is the deuterium and 15N-labeled L-Glutamic acid. L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA) . L-Glutamic acid shows a direct activating effect on the release of DA from dopaminergic terminals.
Product Specifications
UNSPSC
12352211
Target
Apoptosis; Endogenous Metabolite; Ferroptosis; iGluR; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(C([2H])([2H])C([2H])([2H])[C@@]([15NH2])([2H])C(O)=O)=O
Molecular Formula
C5H4D5 15NO4
Molecular Weight
153.15
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
AMPA Receptor
Available Sizes
Frequently Asked Questions
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