Rimtuzalcap
Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels) . Rimtuzalcap can be used for the research of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA) [1].
Product Specifications
CAS Number
[2167246-24-2]
Product Name Alternative
CAD-1883
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/rimtuzalcap.html
Purity
99.27
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
CC1=NN(C2=NC(N3CCOCC3)=CC(NC4CCC(F)(F)CC4)=N2)C=C1
Molecular Formula
C18H24F2N6O
Molecular Weight
378.42
References & Citations
[1]Crystalline forms of potassium channel modulators. WO2020086456A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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