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(1S,2S)-2-PCCA (hydrochloride)

Product Specifications

UNSPSC Description

(1S,2S)-2-PCCA hydrochloride is a less active diastereomer of 2-PCCA. 2-PCCA is a GPR88 receptor agonist, and inhibits GPR88-mediated cAMP production, with an EC50 of 116 nM in HEK293 cells.

Target Antigen

Others

Type

Reference compound

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/_1S,2S_-2-PCCA_hydrochloride_.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC[C@H](C)[C@H](N)CN(C1=CC=C(C2=CC=C(C=C2)CCC)C=C1)C([C@@H]3[C@@H](C4=CC=CC=N4)C3)=O.Cl.Cl

Molecular Weight

528.56

References & Citations

[1]Jin C, et al. Synthesis, pharmacological characterization, and structure-activity relationship studies of small molecular agonists for the orphan GPR88 receptor. ACS Chem Neurosci. 2014 Jul 16;5(7):576-87.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-100013B1/1S-2S-2-PCCA-hydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-100013B1/1S-2S-2-PCCA-hydrochloride-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1609563-70-3

Available Sizes

Curated Selection

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