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JNK-IN-13

JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively[1].

Product Specifications

CAS Number

345986-38-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

JNK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/jnk-in-13.html

Purity

97.60

Solubility

DMSO : ≥ 31 mg/mL

Smiles

ClC1=NC(C(C2=NC3=CC=CC=C3S2)C#N)=CC=N1

Molecular Formula

C13H7ClN4S

Molecular Weight

286.74

Precautions

H302, H315, H319, H335

References & Citations

[1]Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JNK2; JNK3

Available Sizes

Frequently Asked Questions

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