JNK-IN-13
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively[1].
Product Specifications
CAS Number
[345986-38-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
JNK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/jnk-in-13.html
Purity
97.60
Solubility
DMSO : ≥ 31 mg/mL
Smiles
ClC1=NC(C(C2=NC3=CC=CC=C3S2)C#N)=CC=N1
Molecular Formula
C13H7ClN4S
Molecular Weight
286.74
Precautions
H302, H315, H319, H335
References & Citations
[1]Serge Halazy, et al. Benzazole derivatives and their use as JNK modulators. EP1110957A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JNK2; JNK3
Available Sizes
Curated Selection
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