Carbonic anhydrase inhibitor 24

Carbonic anhydrase inhibitor 24 (Compound 11) is a human carbonic anhydrase (carbonic anhydrase) inhibitor. Ki values of Carbonic anhydrase inhibitor 24 for hCAs IX and XII were 10.7 and 7.5 nM, respectively[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-24.html

Solubility

10 mM in DMSO

Smiles

NS(C1=C(Cl)C=C(Cl)C(C(O/N=C/C2=C(OC)C=CC=C2OC)=O)=C1)(=O)=O

Molecular Formula

C16H14Cl2N2O6S

Molecular Weight

433.26

References & Citations

[1]Kilbile J T, Sapkal S B, Renzi G, et al. Novel 2, 4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors. ACS Medicinal Chemistry Letters, 2024.