Aldometanib
Aldometanib (LXY-05-029) is an orally active aldolase inhibitor. Aldometanib can activate lysosomal adenosine monophosphate-activated protein kinase (AMPK) and decreases blood glucose. Aldometanib can be used for the research of metabolic homeostasis[1].
Product Specifications
CAS Number
[2904601-67-6]
Product Name Alternative
LXY-05-029
UNSPSC
12352005
Target
AMPK
Type
Reference compound
Related Pathways
Epigenetics; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aldometanib.html
Purity
99.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CCCCCCCCCCCCCCCCN1C=C[N+](CC2=C(Cl)C=CC=C2Cl)=C1C.[I-]
Molecular Formula
C27H43Cl2IN2
Molecular Weight
593.45
References & Citations
[1]Chen-Song Zhang, et al. The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK. Nat Metab. 2022 Oct 10.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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