Mebeverine (hydrochloride) (Standard)

Mebeverine (hydrochloride) (Standard) is the analytical standard of Mebeverine (hydrochloride) . This product is intended for research and analytical applications. Mebeverine hydrochloride, a β-phenylethylamine derivative, is a musculotropic agent that potently blocks intestinal peristalsis. Mebeverine directly blocks voltage-operated sodium channels and inhibits intracellular calcium accumulation[1][2].

Product Specifications

CAS Number

[2753-45-9]

UNSPSC

12352005

Target

Reference Standards; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/mebeverine-hydrochloride-standard.html

Smiles

O=C(OCCCCN(CC)C(C)CC1=CC=C(OC)C=C1)C2=CC=C(OC)C(OC)=C2.[H]Cl

Molecular Formula

C25H36ClNO5

Molecular Weight

466.01

References & Citations

[1]Den Hertog A, et al. Modification of alpha 1-receptor-operated channels by mebeverine in smooth muscle cells of guinea-pig taenia caeci. Eur J Pharmacol. 1987 Jun 26;138 (3) :367-74.|[2]Annaházi A, et al. Role of antispasmodics in the treatment of irritable bowel syndrome. World J Gastroenterol. 2014;20 (20) :6031-6043.