Tubeimoside III

Tubeimoside III is a triterpenoid saponin. Tubeimoside III has anti-inflammatory and antitumor effects. Tubeimoside III has an LD50 of 15 mg/kg by intraperitoneal injection in ICR mice. Tubeimoside III can be used for the research of tumors and inflammatory diseases[1][2].

Product Specifications

CAS Number

[115810-13-4]

UNSPSC

12352005

Hazard Statement

H302

Target

Interleukin Related; NO Synthase

Type

Natural Products

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tubeimoside-iii.html

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@H]1[C@@]23[C@](CC(C)(C)CC3)([H])C4=CC[C@@]([C@@]5([C@H]([C@@](C)([C@@H](O[C@@]6([H])[C@]([C@H]([C@H](O)[C@@H](CO)O6)O)([H])O[C@]7([H])O[C@@](COC(C[C@](C)(O)CC(O[C@]8([H])[C@@H](O[C@@]9([H])[C@@H]([C@H]([C@H](O)CO9)O)O)[C@@H](O)[C@](O[C@H]8C)([H])O[C@@]%10([H])[C@](OC[C@H](O)[C@@H]%10O)([H])OC2=O)=O)=O)([H])[C@@H](O)[C@H](O)[C@H]7O)[C@@H](O)C5)CO)CC%11)C)([H])[C@]%11(C)[C@]4(C)C1

Molecular Formula

C64H100O31

Molecular Weight

1365.46

Precautions

H302

References & Citations

[1]Yu TX, et al. Structure-activity relationship of tubeimosides in anti-inflammatory, antitumor, and antitumor-promoting effects. Acta Pharmacol Sin. 2001 May;22 (5) :463-8.|[2]Li WH, et al. Tubeimoside III inhibits lipopolysaccharide-induced inflammatory responses by reprogramming glycolytic metabolism. Authorea Preprints. 2024.