Nestoron
Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive[1][2].
Product Specifications
CAS Number
7759-35-5
Product Name Alternative
ST-1435; Elcometrine
UNSPSC
12352211
Hazard Statement
H315-H319-H320
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/nestoron.html
Purity
99.83
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
CC([C@]1(OC(C)=O)[C@@]2([C@]([H])([C@@]3(CCC4=CC(CC[C@@]4([C@]3(CC2)[H])[H])=O)[H])CC1=C)C)=O
Molecular Formula
C23H30O4
Molecular Weight
370.48
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Prasad PV, et al. Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive.Steroids. 2010 Mar;75 (3) :252-64. Epub 2010 Jan 11.|[2]Hussain R, et al. Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology. 2011 Oct;152 (10) :3820-31.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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