Nestoron

Nestoron (ST-1435) is a 19-norprogesterone derivative with high affinity and selectivity for progesterone receptors. Nestoron is a highly selective and potent progestogen that can be used as a hormonal contraceptive[1][2].

Product Specifications

CAS Number

[7759-35-5]

Product Name Alternative

ST-1435; Elcometrine

UNSPSC

12352211

Hazard Statement

H315-H319-H320

Target

Progesterone Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/nestoron.html

Purity

99.83

Solubility

DMSO : 33.33 mg/mL (ultrasonic)

Smiles

CC([C@]1(OC(C)=O)[C@@]2([C@]([H])([C@@]3(CCC4=CC(CC[C@@]4([C@]3(CC2)[H])[H])=O)[H])CC1=C)C)=O

Molecular Formula

C23H30O4

Molecular Weight

370.48

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Prasad PV, et al. Single-dose pharmacokinetics of Nestorone, a potential female-contraceptive.Steroids. 2010 Mar;75 (3) :252-64. Epub 2010 Jan 11.|[2]Hussain R, et al. Progesterone and Nestorone facilitate axon remyelination: a role for progesterone receptors. Endocrinology. 2011 Oct;152 (10) :3820-31.