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CaMKI (299-320)

CaMKI (299-320) refers to a peptide consisting of residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI) . CaMKI (299-320), as a protein kinase, has a high affinity interaction with Ca2+-CAM (Kd≤1 nM≤1 nM), which can phosphorylate specific substrate proteins, thereby regulating their activity. CaMKI (299-320) contains the CAM-binding domain and the self-inhibition domain, and CaMKI (299-320) can be used to study cell physiological processes, including cell proliferation, differentiation, and apoptosis[1].

Product Specifications

CAS Number

205598-38-5

Product Name Alternative

Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain

UNSPSC

12352209

Target

CaMK

Type

Peptides

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/camki-299-320.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CC(N)=O)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C116H192N38O28S

Molecular Weight

2599.07

References & Citations

[1]Yuan T, et al. Spectroscopic characterization of the calmodulin-binding and autoinhibitory domains of calcium/calmodulin-dependent protein kinase I[J]. Archives of biochemistry and biophysics, 2004, 421 (2) : 192-206.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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