Cimetropium (Bromide)
Cimetropium Bromide (DA-3177) is a mAChR antagonist for long-term treatment of irritable bowel syndrome.
Product Specifications
CAS Number
51598-60-8
Product Name Alternative
DA-3177
UNSPSC
12352005
Hazard Statement
H302
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Cimetropium_Bromide.html
Purity
97.46
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
C[N+]1([C@H]2[C@@H](O3)[C@@H]3[C@@H]1C[C@H](OC([C@@H](C4=CC=CC=C4)CO)=O)C2)CC5CC5.[Br-]
Molecular Formula
C21H28BrNO4
Molecular Weight
438.36
Precautions
H302
References & Citations
[1]Identification of orally administered cimetropium bromide in the colon of the rat and its possible local spasmolytic effect.|[2]Saitoh N, et al. Characterization of antimuscarinic effect of cimetropium bromide in guinea pig ileum. J Smooth Muscle Res. 1997 Feb;33 (1) :1-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
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