PPARα agonist 3
PPARα agonist 3 (Compound A229) is a PPARα agonist (EC50: 590 nM). PPARα agonist 3 inhibits TBHP or 4-HNE -induced production of ROS[1].
Product Specifications
UNSPSC
12352005
Target
PPAR; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/pparα-agonist-3.html
Smiles
O=C(O)C1=CC(NCC2=CC=C(C3=CC=C(F)C=C3)C=C2)=CC(F)=C1
Molecular Formula
C20H15F2NO2
Molecular Weight
339.34
References & Citations
[1]Bo Hu, et al. Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators. ACS Medicinal Chemistry Letters Article ASAP
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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