Progesterone-13C3

Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.

Product Specifications

CAS Number

[327048-87-3]

Product Name Alternative

Pregn-4-ene-3,20-dione-13C3

UNSPSC

12352211

Hazard Statement

H351, H360, H362

Target

Endogenous Metabolite; Isotope-Labeled Compounds; Progesterone Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/progesterone-13c3.html

Purity

99.60

Solubility

DMSO : 50 mg/mL (ultrasonic; warming)

Smiles

C[C@@]12[C@]3([H])[C@](CCC1=[13CH][13C]([13CH2]C2)=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C

Molecular Formula

C18 13C3H30O2

Molecular Weight

317.44

Precautions

H351, H360, H362

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Schindler AE, et al. Classification and pharmacology of progestins. Maturitas. 2003 Dec 10;46 Suppl 1:S7-S16.|[3]Zava DT, et al. Estrogen and progestin bioactivity of foods, herbs, and spices. Proc Soc Exp Biol Med. 1998 Mar;217 (3) :369-78.|[4]Komesaroff PA, et al. Effects of wild yam extract on menopausal symptoms, lipids and sex hormones in healthy menopausal women. Climacteric. 2001 Jun;4 (2) :144-50.|[5]Girling JE, et al. Progesterone, but not estrogen, stimulates vessel maturation in the mouse endometrium. Endocrinology. 2007 Nov;148 (11) :5433-41. Epub 2007 Aug 9.