AF/LE Purified Anti-Human CD64 Antibody[10.1]

Product Specifications

Background

CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC) .

Abbreviation

CD64

Gene ID

2209

UniProt

P12314

Host

Mouse

Reactivity

Human

Immunogen

Recombinant Human CD64 protein

Target

FCG; CD antigen CD; Fcgr; FCGR1A; CD64; CD64A; FCRI; IGFR1; CD antigen CD64; CD64A/B/C; Fc fragment of IgG high affinity Ia/b/c receptor; Fc gamma RI; Fc-gamma RI; Fc-gamma RIA; FcgammaRIa; FCGR1A/B/C; High affinity immunoglobulin gamma Fc receptor I; IGFR 1; IgG Fc receptor I; FCG1; FCGR1; Fc&gamma-RI-I; FcR I; CD64a

Clonality

Monoclonal

Clone

10.1

Conjugation

None (AF/LE)

Applications

FCM

Field of Research

Immunology

Purification

>98%, Protein A/G purified

Concentration

≥ 1 mg/mL

Dilution

Buffer

Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.

Shipping Conditions

Ice bag

Storage Conditions

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.