Lamin B Receptor / LBR Recombinant Rabbit Monoclonal Antibody [PSH02-93]
Catalyzes the reduction of the C14-unsaturated bond of lanosterol, as part of the metabolic pathway leading to cholesterol biosynthesis . Plays a critical role in myeloid cell cholesterol biosynthesis which is essential to both myeloid cell growth and functional maturation. Mediates the activation of NADPH oxidases, perhaps by maintaining critical levels of cholesterol required for membrane lipid raft formation during neutrophil differentiation. Anchors the lamina and the heterochromatin to the inner nuclear membrane.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Swiss Prot
Q14739 Human
Cellular Locus
Nucleus inner membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human Lamin B Receptor/LBR aa 1-500 / 615.
Isotype
IgG
Clone
PSH02-93
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HEK-293 cell lysate, HeLa cell lysate, Jurkat cell lysate, HEK-293, human small intestine tissue, human testis tissue.
Concentration
1 mg/mL
Dilution
WB:1:2,000 ;IHC-P:1:1,000-10,000 ;IF-Cell:1:2,000 ;FC:1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 71 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD100 (Semaphorin-4D) (A8), CF488A conjugate, 0.1mg/mL
Complement C4d (C4D204), CF640R conjugate, 0.1mg/mL
Cytokeratin 17 (E3), CF488A conjugate, 0.1mg/mL
CD59 (heavy chain of Protectin) (BRA-10G), CF568 conjugate, 0.1mg/mL
