Ophthalmic acid
Ophthalmic acid, an analogue of GSH, is a marker of oxidative stress and hepatic GSH consumption. Ophthalmic acid is an inhibitor of Glyoxalase I reaction[1][2].
Product Specifications
CAS Number
495-27-2
UNSPSC
12352211
Hazard Statement
H225, H319
Target
Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ophthalmic-acid.html
Concentration
10mM
Purity
99.17
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC(CNC([C@H](CC)NC(CC[C@H](N)C(O)=O)=O)=O)=O
Molecular Formula
C11H19N3O6
Molecular Weight
289.29
Precautions
H225, H319
References & Citations
[1]Gurnit Kaur, et al. Detection of Ophthalmic Acid in Serum from Acetaminophen-Induced Acute Liver Failure Patients Is More Frequent in Non-Survivors. PLoS One. 2015 Sep 25;10 (9) :e0139299. |[2]E E CLIFFE, et al. The mechanism of the glyoxalase I reaction, and the effect of ophthalmic acid as an inhibitor. Biochem J. 1961 Jun;79 (3) :475-82.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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