Atopaxar
Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease[1][2].
Product Specifications
CAS Number
751475-53-3
Product Name Alternative
E5555; ER-172594-00
UNSPSC
12352005
Target
Apoptosis; JAK; Protease Activated Receptor (PAR)
Type
Reference compound
Related Pathways
Apoptosis; Epigenetics; GPCR/G Protein; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/atopaxar.html
Concentration
10mM
Purity
99.87
Solubility
DMSO : ≥ 100 mg/mL
Smiles
COC1=C(N2CCOCC2)C=C(C(CN(CC3=C4C(F)=C(OCC)C(OCC)=C3)C4=N)=O)C=C1C(C)(C)C
Molecular Formula
C29H38FN3O5
Molecular Weight
527.63
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PAR1
Available Sizes
Frequently Asked Questions
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