MOG (35-55) amide, mouse, rat

MOG (35-55) amide, mouse, rat the terminal amidation form of the 35-55 fragment of the myelin oligodendrocyte glycoprotein (MOG) immunogenic peptide (MOG (35-55) (HY-P1240) ) . MOG (35-55) amide, mouse, rat can be used for experimental autoimmune encephalomyelitis (EAE) modeling[1][2][3].

Product Specifications

CAS Number

[2022956-48-3]

UNSPSC

12352209

Target

CCR

Type

Peptides

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/mog-35-55-amide-mouse-rat.html

Purity

99.50

Solubility

H2O : ≥ 100 mg/mL

Smiles

OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N2[C@@H](CCC2)C(N[C@H](C(N[C@@H](CO)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(NCC(N[C@H](C(N)=O)CCCCN)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)NC([C@@H](NC(CNC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@@H](N)CCSC)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O

Molecular Formula

C118H178N36O28S

Molecular Weight

2580.97

References & Citations

[1]Saligrama N, et al. Opposing T cell responses in experimental autoimmune encephalomyelitis. Nature. 2019 Aug;572 (7770) :481-487. |[2]Fabiola Puentes, et al. Characterization of immune response to neurofilament light in experimental autoimmune encephalomyelitis. J Neuroinflammation. 2013 Sep 22:10:118. |[3]2. Delarasse C, et al. Novel pathogenic epitopes of myelin oligodendrocyte glycoprotein induce experimental autoimmune encephalomyelitis in C57BL/6 mice. Immunology. 2013 Dec;140 (4) :456-64.