Piperacetazine
Piperacetazine is an orally active dopamine receptor antagonist and phenothiazine antipsychotic. Piperacetazine can directly bind to the PAX3::FOXO1 fusion protein and inhibit its transcriptional activity. Piperacetazine also exhibits antitumor activity with an IC50 of 7.627 μM against PANC-1 cells. Piperacetazine can be used for the research of diseases such as schizophrenia and pancreatic cancer and other tumors[1][2][3].
Product Specifications
CAS Number
3819-00-9
UNSPSC
12352005
Hazard Statement
H317
Target
CD276/B7-H3; Dopamine Receptor; FOXO
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Piperacetazine.html
Purity
98.03
Solubility
DMSO : ≥ 6 mg/mL|Ethanol : 50 mg/mL (ultrasonic)
Smiles
CC(C(C=C1N2CCCN3CCC(CCO)CC3)=CC=C1SC4=C2C=CC=C4)=O
Molecular Formula
C24H30N2O2S
Molecular Weight
410.57
Precautions
H317
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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