1-Oleoyl lysophosphatidic acid

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) is an abundant lysophosphatidic acid (LPA) species with high biological activity due to its strong affinity for the LPA receptors. 1-Oleoyl lysophosphatidic acid is commonly used in most laboratories as a reagent for LPA receptor activation[1]. 1-Oleoyl lysophosphatidic acid increases SRE-driven β-galactosidase activity[2].

Product Specifications

CAS Number

[65528-98-5]

Product Name Alternative

1-Oleoyl-sn-glycero-3-phosphate; 1-Oleoyl-LPA

UNSPSC

12352211

Hazard Statement

H225, H319

Target

LPL Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/1-oleoyl-lysophosphatidic-acid.html

Concentration

22.91 mM * 500 μL in Ethanol

Purity

99.96

Solubility

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(O)(O)=O)=O

Molecular Formula

C21H41O7P

Molecular Weight

436.52

Precautions

H225, H319

References & Citations

[1]Castilla-Ortega E, et al. 1-Oleoyl lysophosphatidic acid: a new mediator of emotional behavior in rats. PLoS One. 2014;9 (1) :e85348. Published 2014 Jan 7.|[2]Perkins LM, et al. Activation of serum response element-regulated genes by lysophosphatidic acid. Nucleic Acids Res. 1994;22 (3) :450-452.